Page 13 - reflections_dyslipidaemia_newsletter5_2023

REFLECTIONS
Dyslipidaemia
Dyslipidaemia Global Newsletter #5 2023

ACRONYMS:
ACC, American College of Cardiology; apoB, apolipoprotein B; ANGPTL3, angiopoietin-like 3; ASCVD, atherosclerotic cardiovascular
disease; ASR, age standardized rate; BMI, body mass index; CETP, cholesteryl ester transfer protein; CHD, coronary heart disease;
Dyslipidaemia
CI, confidence interval; CRP, c-reactive protein; CTCA, computed tomography coronary angiography; CVD, cardiovascular disease;
DALY, disability-adjusted life-years; EAS, European Atherosclerosis Society; ESC, European Society of Cardiology; FOURIER-
OLE, Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk–Open-Label Extension;
GBD, Global Burden of Disease; HDL, high-density lipoprotein; HoFH, homozygous familial hypercholesterolaemia; HR, hazard
ratio; LALD, lysosomal acid lipase deficiency; LCAT, lecithin:cholesterol acyltransferase; LDL-C, low-density lipoprotein cholesterol;
MACE, major adverse cardiovascular event; MI, myocardial infarction; NGS, next-generation DNA sequencing; OxPL, oxidized
phospholipids; PCSK9i, proprotein convertase subtilisin-kexin type 9 inhibitor; PONI, paraoxonase 1; RCTs, randomized controlled
trials; S1P, sphingosine-1-phosphate; SAA, serum amyloid A; SBP, systolic blood pressure; SD, standard deviation; SDI, Socio-
Demographic Index; SNP, single-nucleotide polymorphism; TIMI, Thrombolysis in Myocardial Infarction; TRL, triglyceride-rich
lipoprotein; WHO, World Health Organization; YLD, years lived with a disability; YLL, years of life lost to due to premature mortality.

TABLE OF CONTENTS